KMID : 0357820080320010068
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Korean Journal of Legal Medicine 2008 Volume.32 No. 1 p.68 ~ p.71
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Change of Surname?: An application of Y-STR Haplotyping
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Seong Ki-Min
Yoo Seong-Yeon Hwang Jung-Ho Cho Nam-Soo Kim Seong-Ho Choi Young-Shik
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Abstract
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Y-STR haplotyping is a powerful forensic and anthropological tool for identifying male lineages. We used high-resolution Y-STR haplotyping to evaluate the possibility of an ancestral relationship between two individuals with the different surname. Of the 17 Y-STRs genotyped, 16 had identical alleles in two individuals, except for an unambiguously sporadic mutation (one-step mutation) at DYS385 locus. The common allele 11.1 (U3Ains) at DYS439 locus was also observed in these two individuals. Sequencing analysis of these alleles of two samples demonstrated an A insertion at base 3 upstream from the repeat region¡¯s first GATA motif. These findings suggested that two individuals were paternally related, even if male individuals live with different surname.
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KEYWORD
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Y-STR, surname, haplotypes, mutation
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